| Grupo | Sintaxe | Tipo | Op | Func | Comentário |
| Transferência de informação | lb Rdest, Imm16(Rsrc) | I | 0x20 | - | load byte |
| lw Rdest, Imm16(Rsrc) | I | 0x23 | - | load word | |
| lbu Rdest, Imm16(Rsrc) | I | 0x24 | - | load unsigned byte | |
| sb Rsrc2, Imm16(Rsrc1) | I | 0x28 | - | store byte | |
| sw Rsrc2, Imm16(Rsrc1) | I | 0x2b | - | store word | |
| lui Rdest, Imm16 | I | 0x0f | - | load upper immediate | |
| mfhi Rdest | R | 00 | 0x10 | move from hi | |
| mflo Rdest | R | 00 | 0x12 | move from lo | |
| mthi Rsrc | R | 00 | 0x11 | move to hi | |
| mtlo Rsrc | R | 00 | 0x13 | move to lo | |
| li Rdest, Imm16/32 | load immediate | ||||
| la Rdest, address16/32 | load address | ||||
| move Rdest, Rsrc | move | ||||
| Operações aritméticas | add Rdest, Rsrc1, Rsrc2 | R | 00 | 0x20 | addition (with overflow) |
| addi Rdest, Rsrc1, Imm16 | I | 08 | - | addition imm. (with ov.) | |
| addu Rdest, Rsrc1, Rsrc2 | R | 00 | 0x21 | addition (without overflow) | |
| addiu Rdest, Rsrc1, Imm16 | I | 09 | - | addition imm. (without ov.) | |
| sub Rdest, Rsrc1, Rsrc2 | R | 00 | 0x22 | subtract (with overflow) | |
| subu Rdest, Rsrc1, Rsrc2 | R | 00 | 0x23 | subtract (without overflow) | |
| mult Rsrc1, Rsrc2 | R | 00 | 0x18 | multiply | |
| multu Rsrc1, Rsrc2 | R | 00 | 0x19 | unsigned multiply | |
| div Rsrc1, Rsrc2 | R | 00 | 0x1a | divide | |
| divu Rsrc1, Rsrc2 | R | 00 | 0x1b | unsigned divide | |
| abs Rdest, Rsrc | absolutevalue | ||||
| mul Rdest, Rsrc1, Rsrc2 | multiply | ||||
| div Rdest, Rsrc1, Rsrc2 | divide | ||||
| rem Rdest, Rsrc1, Rsrc2 | remainder | ||||
| Operações lógicas e de comparação | and Rdest, Rsrc1, Rsrc2 | R | 00 | 0x24 | AND |
| andi Rdest, Rsrc1, Imm16 | I | 0x0c | - | AND immediate | |
| or Rdest, Rsrc1, Rsrc2 | R | 00 | 0x25 | OR | |
| ori Rdest, Rsrc1, Imm16 | I | 0x0d | - | OR immediate | |
| xor Rdest, Rsrc1, Rsrc2 | R | 00 | 0x26 | XOR | |
| xori Rdest, Rsrc1, Imm16 | I | 0x0e | - | XOR immediate | |
| nor Rdest, Rsrc1, Rsrc2 | R | 00 | 0x27 | NOR | |
| slt Rdest, Rsrc1, Rsrc2 | R | 00 | 0x2a | set less than | |
| slti Rdest, Rsrc1, Imm16 | I | 0x0a | - | set less than immediate | |
| sltu Rdest, Rsrc1, Rsrc2 | R | 00 | 0x2b | set less than unsigned | |
| sltiu Rdest, Rsrc1, Imm16 | I | 0x0b | - | set less than unsigned imm. | |
| not Rdest, Rsrc | not | ||||
| Operações de deslocamento de bits | sll Rdest, Rsrc1, Rsrc2 | R | 00 | 00 | shift left logical |
| srl Rdest, Rsrc1, Rsrc2 | R | 00 | 02 | shift right logical | |
| sra Rdest, Rsrc1, Rsrc2 | R | 00 | 03 | shift right arithmetic | |
| rol Rdest, Rsrc1, Rsrc2 | rotate left | ||||
| ror Rdest, Rsrc1, Rsrc2 | rotate right | ||||
| Operações de salto | j address28 | J | 02 | - | jump (absolute addr) |
| jr Rsrc | R | 00 | 08 | jump register | |
| beq Rsrc1, Rsrc2, address18 | I | 04 | - | branch on equal (relative addr) | |
| bne Rsrc1, Rsrc2, address18 | I | 05 | - | branch on not equal (relative addr) | |
| bgez Rsrc, address18 | I | 01 | 01* | br. on greater than equal zero (relative addr) | |
| bgtz Rsrc, address18 | I | 07 | - | br. on greater than zero (relative addr) | |
| blez Rsrc, address18 | I | 06 | - | br. on less than equal zero (relative addr) | |
| bltz Rsrc, address18 | I | 01 | 00* | br. on less than zero (relative addr) | |
| jal address28 | J | 03 | - | jump and link (absolute addr) | |
| jalr Rsrc | R | 00 | 09 | jump and link register | |
| b address18/32 | branch inconditional (relative addr) | ||||
| b<cnd> Rsrc1, Rsrc2, address18/32 | br. on <cnd> = [gt, ge, lt, le] (relative addr) | ||||
| b<cnd>u Rsrc1, Rsrc2, address18/32 | br. on <cnd> = [gt, ge, lt, le] uns (relative addr) | ||||
| Excepção | rfe | R | 0x10 | 0x20 | return from exception |
| syscall | R | 00 | 0x0c | system call | |
| break code20 | R | 00 | 0x0d | break |
* especificado no campo rt
| Instrução | Tipo | Op/6 bits | Rs/5 bits | Rt/5 bits | Rd/5 bits | shamt/5 bits | Func/6 bits |
| add $a0, $t0, $s0 | R | 0 | 8 ($t0) | 0x10 ($s0) | 4 ($a0) | 0 | 0x20 |
| addi $8, $9, 0x100 | I | 8 | 9 | 8 | 0x100 | ||
| sw $6, -4 ($7) | I | 0x2b | 7 | 6 | 0xfffc (-4) | ||
| beq $4, $5, 0x40 | I | 4 | 4 | 5 | 0x10 (0x40/4) | ||
| j 0x80000 | J | 2 | 0x20000 (0x8000/4) | ||||